Physiological Stress Modelling and Hemolysis Prediction for High Shear Stress Flows using Computational Hemodynamics

نویسندگان

چکیده

Predicting hemolysis is a mandatory task when designing blood flow related mechanisms. For decades, researchers have tried to estimate trauma in red cell (RBC) for applying assist mechanisms development, but the specificity and absence of more physical details limited models this purpose into ranges applications. This work aims present new method modelling considering stress threshold that RBC could stand and, bellow that, Physiological Stress. Complementing application, simulations Ventricular Assist Device (VAD) was performed using Computational Fluid Dynamics (CFD) hemodynamics. risk analyses, critical regions were established by mean magnitude, also purposed here. The magnitude presented including turbulent parameters, trying reduce error calculating tensor velocity magnitudes Reynolds Average Navier-Stokes flows. Five tested: Standard κ-ε, κ-ε RNG, Realizable, κ-ω, κ-ω SST Spalart-Allmaras models. Results indicate similar results Stress compared traditional model applications, even adapted coefficients, what induces specific coefficients might improve estimations. RNG had better agreement with data expectations best scenarios improved future uses.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Polymer stress tensor in turbulent shear flows.

The interaction of polymers with turbulent shear flows is examined. We focus on the structure of the elastic stress tensor, which is proportional to the polymer conformation tensor. We examine this object in turbulent flows of increasing complexity. First is isotropic turbulence, then anisotropic (but homogenous) shear turbulence, and finally wall bounded turbulence. The main result of this pap...

متن کامل

Stress-controlled elastic granular shear flows

While many rheological studies are performed at a fixed concentration, most granular flows are constrained, not by concentration, but by an applied stress. The stress constraint sets the average concentration, but the material is free to vary that concentration slightly to match the applied stress with that generated internally. This study examines stress-controlled systems in light of recent f...

متن کامل

MEMS-based pressure and shear stress sensors for turbulent flows

From a fluid dynamics perspective, the introduction of microelectromechanical systems (MEMS) has considerably broadened the spectrum of workable experiments. A typical MEMS sensor is at least one order of magnitude smaller than traditional sensors used to measure instantaneous flow quantities such as pressure and velocity. The microsensors can resolve all relevant scales even in high-Reynolds-n...

متن کامل

A Review of Reynolds Stress Models for Turbulent Shear Flows

A detailed review of recent developments in Reynolds stress modeling for incompressible turbulent shear ows is provided. The mathematical foundations of both two-equation models and full second-order closures are explored in depth. It is shown how these models can be systematically derived for two-dimensional mean turbulent ows that are close to equilibrium. A variety of examples are provided t...

متن کامل

Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient.

BACKGROUND AND PURPOSE Cerebral aneurysms are preferentially located at arterial curvatures and bifurcations that are exposed to major hemodynamic forces, increasingly implicated in the life cycle of aneurysms. By observing the natural history of aneurysm formation from its preaneurysm state, we aimed to examine the hemodynamic microenvironment related to aneurysm initiation at certain arterial...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Applied Fluid Mechanics

سال: 2021

ISSN: ['1735-3572', '1735-3645']

DOI: https://doi.org/10.47176/jafm.14.04.32211